Respiratory organoid development via tailored three-dimensional macromolecular environments: a 3DbioNet funded project
Professor Ruth Cameron’s team at the University of Cambridge was awarded pump priming grant by 3DbioNet. The aim of the study is to produce alveolar organoid structures in highly defined 3D structures. This will allow transitioning away from current spherical organoid systems, typically cultured using Matrigel, to a 3D system that more appropriately reflects tissue organisation. The group propose to design ice –templated, collagen- and elastin-based, porous environments to supply the spatial, mechanical and biochemical cues of native tissue.Below is a video we filmed from our trip to their laboratory in Cambridge.